Evidence-based medicine, continuous innovation
CISPOLY emphasizes the evidence base and clinical research of methylation applications, conducting multiple prospective multi-center clinical trials with numerous publications.
Reply to: Comments on "Enhanced Diagnostic Accuracy of High-Grade Cervical Intraepithelial Neoplasia in Postmenopausal Women Through PAX1/JAM3 Methylation Analysis"
Journal: International Journal of Cancer
Affiliation: Changsha Blood Center
DOI: 10.1002/ijc.70484
Effectiveness analysis and clinical application potential exploration of combined detection of PAX1/JAM3 gene methylation in early diagnosis of cervical precancerous lesions
Journal: Clinical Epigenetics
Affiliation: Tumor Hospital Affiliated to Xinjiang Medical University
DOI: 10.1186/s13148-026-02095-z
PAX1/JAM3 methylation - a novel biomarker for early detection and accurate management of cervical adenocarcinoma
Journal: American Journal of Cancer Research
Affiliation: The 940th Hospital of Joint Logistics Support Force of PLA
DOI: 10.62347/SATU5579
Diagnostic testing accuracy of DNA methylation tests for detection of high-grade cervical intraepithelial neoplasia and cervical cancer: A systematic review and meta-analysis
Journal: European Journal of Cancer
Affiliation: Imperial College London
DOI: 10.1016/j.ejca.2026.116823
Association of PAX1/JAM3 gene methylation, HR-HPV, and TCT with high-grade cervical lesions in a high-risk cohort: a multinomial logistic regression analysis
Journal: BMC Women's Health
Affiliation: First Hospital of Hebei Medical University
DOI: 10.1186/s12905-026-04622-9
Preliminary study on PAX1/JAM3 methylation and HPV viral load in CIN3-like squamous cell carcinoma: Are there differences from CIN3 and early invasive carcinoma?
Journal: Clinical Epigenetics
Affiliation: Peking University People's Hospital
DOI: 10.1186/s13148-026-02201-1
Validation of a cervical CDO1/CELF4 methylation test for endometrial cancer: a prospective paired-sample comparison with intrauterine specimens
Journal: Frontiers in Medicine
Affiliation: Gansu Provincial Maternity and Child-care Hospital
DOI: 10.3389/fmed.2026.1690020
Diagnostic Accuracy and Concordance of Self-Collected Cervical CDO1 and CELF4 Methylation Testing Compared With Physician Sampling for Endometrial Cancer
Journal: JCO Precision Oncology
Affiliation: The Second Xiangya Hospital of Central South University
DOI: 10.1200/PO-25-01081
CDO1 and CELF4 methylation assay as the dominant predictor of endometrial cancer: A cohort analysis across pre- and post-menopausal cohorts
Journal: Gynecologic Oncology
Affiliation: Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University)
DOI: 10.1016/j.ygyno.2026.01.776
Enhanced diagnostic accuracy of high-grade cervical intraepithelial neoplasia in postmenopausal women through PAX1/JAM3 methylation analysis
Journal: International Journal of Cancer
Affiliation: The First Hospital of Hunan University of Chinese Medicine
DOI: 10.1002/ijc.70245
Diagnostic value of PAX1/JAM3 gene methylation for cervical cancer in HR-HPV-infected women
Journal: Labeled Immunoassays and Clinical Medicine
Affiliation: Beijing Obstetrics and Gynecology Hospital, Capital Medical University (Beijing Maternal and Child Health Care Hospital)
DOI: 10.11748/bjmy.issn.1006-1703.2025.10.008
Application of PAX1/JAM3 dual-gene methylation in cervical cancer screening and treatment
Journal: International Journal of Obstetrics and Gynecology
Affiliation: The Second Affiliated Hospital of Shandong First Medical University
DOI: 10.12280/gjfckx.20250484
Preliminary study on the predictive value of PAX1 and JAM3 gene methylation in cervical exfoliated cells for cervical intraepithelial neoplasia
Journal: Journal of Hunan Normal University (Medical Sciences)
Affiliation: Changsha Maternal and Child Health Hospital
The performance of JAM3/PAX1 methylation in the diagnosis of high-grade squamous intraepithelial lesions for women with high-risk HPV infection
Journal: BMC cancer
Affiliation: The Third Xiangya Hospital of Central South University
DOI: 10.1186/s12885-024-13299-y
Triage performance of PAX1m/JAM3m in opportunistic cervical cancer screening of non-16/18 human papillomavirus-positive women: a multicenter prospective study
Journal: Clinical Epigenetics
Affiliation: Peking Union Medical College Hospital
DOI: 10.1186/s13148-024-01731-w
The endometrial cancer detection using non-invasive hypermethylation of CDO1 and CELF4 genes in women with postmenopausal bleeding in Northwest China
Journal: CytoJournal
Affiliation: Gansu Provincial Maternity and Child-care Hospital
DOI: 10.25259/Cytojournal_78_2023
DNA methylation detection is a significant biomarker for screening endometrial cancer in premenopausal women with abnormal uterine bleeding
Journal: International Journal of Gynecological Cancer
Affiliation: The Third Xiangya Hospital, Central South University
DOI: 10.1136/ijgc-2024-005723
High-grade cervical lesions diagnosed by JAM3/PAX1 methylation in high-risk human papillomavirus-infected patients
Journal: Journal of Central South University (Medical Sciences)
Affiliation: The Third Xiangya Hospital of Central South University
DOI: 10.11817/j.issn.1672-7347.2023.230175